Michael Behe

Michael Joseph Behe is an American biochemist and an advocate of the pseudoscientific principle of intelligent design.
Behe serves as professor of biochemistry at Lehigh University in Bethlehem, Pennsylvania, and as a senior fellow of the Discovery Institute's Center for Science and Culture. He advocates for the validity of the argument for irreducible complexity, which claims that some biochemical structures are too complex to be explained by known evolutionary mechanisms and are therefore probably the result of intelligent design. Behe has testified in several court cases related to intelligent design, including the court case Kitzmiller v. Dover Area School District, where his views were cited in the ruling that intelligent design is not science and is religious in nature.
Behe's claims about the irreducible complexity of essential cellular structures have been rejected by the majority of the scientific community.

Early life and education

Behe was born in Altoona, Pennsylvania, and grew up in Harrisburg, Pennsylvania, where he graduated from Bishop McDevitt High School. He graduated from Drexel University in Philadelphia in 1974 with a B.S. in chemistry. He received his Ph.D. in biochemistry at the University of Pennsylvania in 1978 for his dissertation research on sickle-cell disease.
From 1978 to 1982, he did postdoctoral work on DNA structure at the National Institutes of Health. From 1982 to 1985, he was assistant professor of chemistry at Queens College in New York City, where he met his wife, Celeste. In 1985, he moved to Lehigh University in Bethlehem, Pennsylvania, where he is currently a professor of biochemistry. From 2005 to 2024, Lehigh University's department of biological sciences exhibited a position statement on its website stating that its faculty reject Behe's views on evolution:
As of 2024, his faculty webpage states: "My arguments about irreducible complexity and intelligent design are my own, and are not endorsed either by Lehigh University in general or by the Department of Biological Sciences in particular." Behe said that the university' biology department gave no scientific evidence that intelligent design "has no basis in science".

Career

Behe says he once fully accepted the scientific theory of evolution, but that after reading Evolution: A Theory in Crisis, by Michael Denton, he came to question evolution. Later, Behe came to believe that there was evidence, at a biochemical level, that some biological systems were "irreducibly complex". He thought that these systems could not, even in principle, have evolved by natural selection. He believed that the only possible alternative explanation for such complex structures was that they were created by an "intelligent designer". Irreducible complexity has been rejected by the scientific community.
The 1987 Edwards v. Aguillard U.S. Supreme Court decision barred the required teaching of creation science from public schools but allowed evolutionary theory on the grounds of scientific validity. After the decision, a later draft of the textbook Of Pandas and People systematically replaced each and every cognate of the word "creation" with the phrase "intelligent design" or similar ID terms. The books of lawyer Phillip E. Johnson on theistic realism dealt directly with criticism of evolutionary theory and its purported biased "materialist" science, and aimed to legitimize the teaching of creationism in schools. In March 1992, a conference at Southern Methodist University brought Behe together with other leading figures into what Johnson later called the "wedge strategy." In 1993, the "Johnson-Behe cadre of scholars" met at Pajaro Dunes, California, and Behe presented for the first time his idea of irreducibly complex molecular machinery. Following a summer 1995 conference, "The Death of Materialism and the Renewal of Culture," the group obtained funding through the Discovery Institute.
For the 1993 edition of Pandas, Behe wrote a chapter on blood clotting, presenting arguments which he later presented in very similar terms in a chapter in his 1996 book Darwin's Black Box. Behe later agreed that they were essentially the same when he defended intelligent design at the Dover trial.
In 1996, Behe became a senior fellow of the Discovery Institute's Center for the Renewal of Science and Culture, later renamed the Center for Science and Culture, an organization dedicated to promoting intelligent design.

''Darwin's Black Box''

In 1996, Behe published his ideas on irreducible complexity in his book Darwin's Black Box. Behe's refusal to identify the nature of any proposed intelligent designer frustrates scientists, who see it as a move to avoid any possibility of testing the positive claims of ID while allowing him and the intelligent design movement to distance themselves from some of the more overtly religiously motivated critics of evolution.
As to the identity of the intelligent designer, Behe responds that if, deep in the woods, one were to come across a group of flowers that clearly spelled out the name "LEHIGH", one would have no doubt that the pattern was the result of intelligent design. Determining who the designer was, however, would not be nearly as easy.
In 1997, Russell Doolittle, on whose work Behe based much of the blood-clotting discussion in Darwin's Black Box, wrote a rebuttal to the statements about irreducible complexity of certain systems. In particular, Doolittle mentioned the issue of the blood clotting in his article, "A Delicate Balance." Later on, in 2003, Doolittle's lab published a paper in the peer-reviewed journal Proceedings of the National Academy of Sciences which demonstrates that the pufferfish lacks at least three out of 26 blood clotting factors, yet still has a workable blood clotting system. According to Doolittle, this defeats a key claim in Behe's book, that blood clotting is irreducibly complex.
In reviewing a book by Robert T. Pennock, Behe took issue with the "intelligent design" group being associated with "creationism," saying readers would typically take that to mean biblical literalism and young Earth creationism. In 2001 Pennock responded that he had been careful to represent their views correctly, and that while several leaders of the intelligent design movement were young Earth creationists, others including Behe were "old-earthers" and "creationists in the core sense of the term, namely, that they reject the scientific, evolutionary account of the origin of species and want to replace it with a form of special creation."

Behe and Snoke article

In 2004, Behe published a paper with David Snoke, in the scientific journal Protein Science that uses a simple mathematical model to simulate the rate of evolution of proteins by point mutation, which he states supports irreducible complexity, based on the calculation of the probability of mutations required for evolution to succeed. However, the paper does not mention intelligent design nor irreducible complexity, which were removed, according to Behe, at the behest of the reviewers. Nevertheless, the Discovery Institute lists it as one of the "Peer-Reviewed & Peer-Edited Scientific Publications Supporting the Theory of Intelligent Design."
Michael Lynch authored a response, to which Behe and Snoke responded. Protein Science discussed the papers in an editorial.
Numerous scientists have debunked the work, pointing out that not only has it been shown that a supposedly irreducibly complex structure can evolve, but that it can do so within a reasonable time even subject to unrealistically harsh restrictions, and noting that Behe and Snoke's paper does not properly include natural selection and genetic redundancy. When the issue raised by Behe and Snoke is tested in the modern framework of evolutionary biology, numerous simple pathways to complexity have been shown. In their response, Behe and Snoke assumed that intermediate mutations are always damaging, where modern science allows for neutral or positive mutations. Some of the critics have also noted that the Discovery Institute continues to claim the paper as 'published evidence for design,' despite its offering no design theory nor attempting to model the design process, and therefore not providing an alternative to random chance.
Many of Behe's statements have been challenged by biologist Kenneth R. Miller in his book, Finding Darwin's God. Behe has subsequently disputed Miller's points in an online essay.

''The Edge of Evolution''

In 2007, Behe's book The Edge of Evolution was published arguing that while evolution can produce changes within species, there is a limit to the ability of evolution to generate diversity, and this limit is somewhere between species and orders.
In this book Behe's central assertion is that Darwinian evolution actually exists but plays only a limited role in the development and diversification of life on Earth. To this aim, he examines the genetic changes undergone by the malaria plasmodium genome and the human genome in response to each other's biological defenses, and identifies that "the situation resembles trench warfare, not an arms race", by considering the hemoglobin-destroying, protein pump-compromising as a "war by attrition". Starting from this example, he takes into account the number of mutations required to "travel" from one genetic state to another, as well as population size for the organism in question. Then, Behe calculates what he calls the "edge of evolution", i.e., the point at which Darwinian evolution would no longer be an efficacious agent of creative biological change, arguing that purposeful design plays a major role in the development of biological complexity, through the mechanism of producing "non-random mutations", which are then subjected to the sculpting hand of natural selection.
The book was reviewed, by prominent scientists in The New York Times, The New Republic, The Globe and Mail, Science, and Nature who were highly critical of the work noting that Behe appears to accept almost all of evolutionary theory, barring random mutation, which is replaced with guided mutation at the hand of an unnamed designer. The book earned Behe the Pigasus Award for the year 2007.