List of sign languages by number of native signers
The following are sign languages reported to be spoken by at least 10,000 people. Additional languages, such as Chinese Sign Language, are likely to have more speakers, but no data is available. Estimates for sign language use are very crude, and definitions of what counts as proficiency varied. For most sign languages, there are no concrete estimate. For instance, it has been reported there are a million signers in Ethiopia, but there are only a fifth that number of deaf people, less than half of whom are fluent in sign, and in addition it is unknown how many different sign languages they use.
| Language | Family or origin | Legal recognition and where spoken natively by significant population | Ethnologue estimate |
| Indo-Pakistani Sign Language | Related to Nepalese Sign Language and possibly other sign languages of the region | No legal recognition. Native to India, Pakistan and Bangladesh. | 1,500,000 in India |
| American Sign Language | Old French Sign Language and Martha's Vineyard Sign Language | ≈ 500,000 in the USA | |
| Brazilian Sign Language | Language isolate | Legally recognized by law 10.436, April 24, 2002 - Native to Brazil. | 200,000 |
| Russian Sign Language | French Sign Language family | Native to Russia, Ukraine, Belarus, Kazakhstan, Moldova, Bulgaria; partly in Latvia, Estonia, Lithuania. | 120,000 |
| Japanese Sign Language | JSL Family | Native to Japan. | 60,000 or 320,000 |
| Mexican Sign Language | French Sign Language family | Native to Urban Mexico. | 130,000 |
| French Sign Language | French Sign Language family. Descended from Old French Sign Language | Native to France. Spoken in Switzerland, Mali, Rwanda, Democratic Republic of the Congo, Togo, Vietnam | 100,000 |
| British Sign Language | BANZSL | Native to United Kingdom. | 80,000 |
| German Sign Language | German Sign Language family | Native to Germany. | 80,000 |
| Malaysian Sign Language | French: ASL | 60,000 | |
| Spanish Sign Language | Unknown origin. | Officially recognized by Spanish Government. Native to Spain except Catalonia and Valencia. | 45,000 |
| Polish Sign Language | German Sign Language family | Native to Poland. | 38,000 to 50,000 signers |
| Italian Sign Language | American | Recognized language in Sicily. | 40,000 |
| Yugoslav Sign Language | French: Austro-Hungarian | Slovenia, Croatia, Bosnia, Serbia | 22,000 |
| Hong Kong Sign Language | Chinese | 20,000 | |
| Dutch Sign Language | French | 15,000 | |
| Auslan | BANZSL | Native to Australia. | 10,000 |