| Name | Developer | Publisher | Genre | Operating system | Date released | - | - | - | - |
| Rage | id Software | Bethesda Softworks | First-person shooter, action-adventure, vehicular combat, racing | Microsoft Windows | | - | - | - | - |
| Railroad Tycoon | MicroProse | MicroProse | Business simulation | MS-DOS, Amiga, macOS, Atari ST | | - | - | - | - |
| Railroad Tycoon 3 | PopTop Software | Gathering of Developers | Business simulation | Microsoft Windows, macOS | | - | - | - | - |
| Rain World | Videocult | Akupara Games, Adult Swim Games | Platform, survival | Microsoft Windows | March 28, 2017 | - | - | - | - |
| Rayman | Ubisoft | Ubisoft | Platformer | MS-DOS | | - | - | - | - |
| Rayman 2: The Great Escape | Ubisoft | Ubisoft | Platformer | Microsoft Windows | | - | - | - | - |
| Rayman 3: Hoodlum Havoc | Ubisoft | Ubisoft | Platformer | Microsoft Windows | | - | - | - | - |
| Rayman Legends | Ubisoft | Ubisoft | Platformer | Microsoft Windows | | - | - | - | - |
| Rayman M/Arena | Ubisoft | Ubisoft | Party | Microsoft Windows | | - | - | - | - |
| Rayman Origins | Ubisoft | Ubisoft | Platformer | Microsoft Windows | | - | - | - | - |
| Recettear: An Item Shop's Tale | EasyGameStation | Carpe Fulgur | RPG | Microsoft Windows | | - | - | - | - |
| Rec Room | Against Gravity | Against Gravity | Action RPG, first-person shooter | Microsoft Windows | | - | - | - | - |
| Roblox Rivals | Nosniy Games | Roblox Corporation | First-person shooter, multiplayer shooter, competitive shooter | Microsoft Windows, iOS, Console | | - | - | - | - |
| Red Orchestra: Ostfront 41-45 | Tripwire Interactive | Bold Games | Tactical shooter, first-person shooter | Microsoft Windows, Linux, macOS | | - | - | - | - |
| Red Dead Redemption | Double Eleven | Rockstar Games | Action-adventure | Microsoft Windows | | - | - | - | - |
| Red Dead Redemption 2 | Rockstar Studios | Rockstar Games | Action-adventure | Microsoft Windows | | - | - | - | - |
| Red Orchestra 2: Heroes of Stalingrad | Tripwire Interactive | 1C Company | Tactical shooter, first-person shooter | Microsoft Windows | | - | - | - | - |
| Redshirt | The Tiniest Shark | Positech Games | Simulation game | Microsoft Windows | | - | - | - | - |
| Reign of Kings | CodeHatch | | Sandbox, first-person shooter | Microsoft Windows | | - | - | - | - |
| Resident Evil | Capcom | Capcom | Survival horror | Microsoft Windows | | - | - | - | - |
| Resident Evil 2 | Capcom | Capcom | Survival horror | Microsoft Windows | | - | - | - | - |
| Resident Evil 3: Nemesis | Capcom | Capcom | Survival horror | Microsoft Windows | | - | - | - | - |
| Resident Evil 4 | Capcom Production Studio 4 | Capcom | Survival horror | Microsoft Windows | | - | - | - | - |
| Resident Evil 5 | Capcom | Capcom | Action-adventure, third-person shooter | Microsoft Windows | | - | - | - | - |
| Resident Evil 6 | Capcom | Capcom | Action-adventure, third-person shooter | Microsoft Windows | | - | - | - | - |
| Resident Evil: Operation Raccoon City | Slant Six Games, Capcom | Capcom | Action-adventure, third-person shooter | Microsoft Windows | | - | - | - | - |
| Resident Evil: Revelations | Capcom, Tose Co. Ltd | Capcom | Action, survival horror | Microsoft Windows | | - | - | - | - |
| Resident Evil: Revelations 2 | Capcom | Capcom | Action, survival horror | Microsoft Windows |
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