4C-B
4C-B, also known as 4C-DOB or DOB-B, as well as 4-bromo-2,5-dimethoxy-α-ethylphenethylamine, is a lesser-known psychedelic drug of the phenethylamine, phenylisobutylamine, and 4C families related to 2C-B and DOB. It is a reasonably potent 5-HT2A receptor partial agonist with a Ki of 7.6nM, but has relatively low efficacy. It is briefly mentioned in Alexander Shulgin's 1991 book PiHKAL, but was never tested by Shulgin. Subsequently, the drug was tested by Daniel Trachsel and colleagues, and was found to be active in a dose range of 50 to 80mg with a duration of around 8hours. It produced pronounced psychedelic effects, though with generally milder effects than 2C-B or DOB. 4C-B is a controlled substance in Canada under phenethylamine blanket-ban language, but is not explicitly controlled in the United States.