Small nucleolar RNA TBR5
In molecular biology, TBR5 is a member of the C/D class of snoRNA which contain the C and D box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Together with TBR7 and TBR17 it is a part of a tandemly repeated snoRNA gene cluster, located within the spliced leader RNA. The cluster genes are produced as polycistronic RNA.