Methyl-TMA


Methyl-TMA, or N-methyl-TMA, also known as N-methyl-3,4,5-trimethoxyamphetamine, is a psychedelic drug of the phenethylamine, amphetamine, and 3C families. It is the N-methyl derivative of 3,4,5-trimethoxyamphetamine as well as the α,N-dimethyl derivative of mescaline.

Use and effects

N-Methylation of psychedelic phenethylamines has invariably greatly reduced or eliminated their hallucinogenic activity. Examples of this include related compounds like Beatrice and methyl-DOB, which at assessed doses appear to be inactive as psychedelics in humans. According to Alexander Shulgin in his book PiHKAL however, methyl-TMA showed "some mental disturbances" at the highest assessed dose of 240mg. For comparison, the active dose range of TMA is 100 to 250mg.

Interactions

History

Methyl-TMA was first described in the scientific literature by at least 1984. It was subsequently described further by Shulgin in PiHKAL in 1991.

Society and culture

Legal status

Canada

Methyl-TMA is a controlled substance in Canada under phenethylamine blanket-ban language.