Lutidine

Lutidine is the trivial name used to describe the chemical compounds which are dimethyl derivatives of pyridine. They were discovered in Dippel's oil and named by Thomas [Anderson (chemist)|Thomas Anderson] in 1851. Their chemical properties resemble those of pyridine, although the presence of the methyl groups may prohibit some of the more straightforward reactions. Lutidine comes in several isomers:

All isomers share the molecular weight 107,16 g/mol and the chemical formula C₇H₉N.

Applications

3,4-Lutidine has formal application in the synthesis of a large bevy of benzomorphan opioid analgesics including: Metazocine, Phenazocine, Ketazocine, Pentazocine, Tonazocine, Volazocine, Cyclazocine, Alazocine, 8-Carboxamidocyclazocine, Fluorophen, Quadazocine, ID-1229, LP-1, MR-2034 .
2,3-Lutidine has application in the synthesis of Rabeprazole, Lansoprazole, Ilaprazole