Margaret Kelly

• Margaret Kelly (civil servant), acting director of the United States Mint by 1911
• Margaret B. Kelly, American accountant and politician from Missouri
• Margaret Kelly (dancer), Irish dancer and the founder of the Bluebell Girls dance troupe
• Margaret Kelly (swimmer), British swimmer
• Margaret Kelly (pharmacologist), American pharmacologist
• Margaret Skillion, sister of Australian bushrangers Ned Kelly and Dan Kelly
• Margaret Kelly, first wife of Bill Murray