James Horton
James Horton may refer to:
- James "Africanus" Beale Horton British Army officer; his Igbo father was freed from slavery in Sierra Leone.
- James Horton (footballer, born 1907), English footballer with Aldershot, Millwall and Southampton
- James Horton (footballer, born 1909) English footballer with Newark, Bradford City and Boston
- James Horton (Medal of Honor, 1864) Union Navy sailor who received the Medal of Honor for bravery
- James Horton (Medal of Honor, 1879), United States Navy sailor who received the Medal of Honor for bravery
- James Edwin Horton, judge in Alabama
- James Horton (Highlander), fictional character from Highlander: The Series
- Jimmy Horton, American racecar driver