Gidazepam

Gidazepam, also known as hydazepam or hidazepam, is a drug which is an atypical benzodiazepine derivative, developed in the Soviet Union. It is a selectively anxiolytic benzodiazepine. It also has therapeutic value in the management of certain cardiovascular disorders.

Pharmacology

Gidazepam and several of its analogs, in contrast to other benzodiazepines, are comparatively more selective agonists of TSPO than the benzodiazepine receptor.
Gidazepam acts as a prodrug to its active metabolite 7-bromo-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one. Its anxiolytic effects can take several hours to manifest presumably due to its slow metabolism. The onset and intensity of anxiolytic effects correlate with blood levels of desalkylgidazepam.
Image:Desalkylgidazepam.svg|class=skin-invert-image|200px|thumb|left|Gidazepam active metabolite, responsible for its therapeutic effects