FC
- Container ship
- EA Sports FC
- FC (band)
- FC TV
- FC connector
- Facilitated communication
- Fact-checking
- Fairchild FC
- Family Computer
- Female condom
- Fergusson College
- Ferrocenyl
- Fibre Channel
- Fielder's choice
- File Compare
- Finncomm Airlines
- Fire Controlman
- First-class cricket
- Flash controller
- Flucytosine
- Foot-candle
- Football club (association football)
- Formal charge
- Forward caste
- Fragment crystallizable region
- Franking credit
- FranklinCovey
- Freedom Club
- Frontier Corps
- Fucked Company
- Fuel cell
- Full combo
- Functional conversation
- Further Confusion
- Holden FC
- Honda Civic (tenth generation)
- Mazda RX-7
- Province of Forlì-Cesena
- U.S. Army Futures Center