Ethyl formate

Ethyl formate is an ester formed when ethanol reacts with formic acid. Ethyl formate has the characteristic smell of rum and is partially responsible for the flavor of raspberries, occurring naturally in some plant oils, fruits, and juices.

Exposure

Ethyl formate is generally recognized as safe by the U.S. Food and Drug Administration.
According to the U.S Occupational Safety and Health Administration, ethyl formate can irritate eyes, skin, mucous membranes, and the respiratory system of humans and other animals; it is also a central nervous system depressant. In industry, it is used as a solvent for cellulose nitrate, cellulose acetate, oils, and greases. It can be used as a substitute for acetone; workers may also be exposed to it under the following circumstances:

during spray, brush, or dip applications of lacquers
during the manufacture of safety glass
when fumigating tobacco, cereals, and dried fruits

OSHA considers a time-weighted average of 100 parts per million over an eight-hour period as the permissible exposure limit. The U.S. National Institute for Occupational Safety and Health also considers a time-weighted average of 100 ppm over an eight-hour period as the recommended exposure limit.

In space

Ethyl formate has been identified in dust clouds in an area of the Milky Way galaxy called Sagittarius B2. It is among 50 molecular species identified using the 30 metre IRAM radiotelescope.