16th Independent Spirit Awards
The 16th Independent Spirit Awards, honoring the best in independent filmmaking for 2000, were announced on March 24, 2001. It was hosted by John Waters.
Special awards
John Cassavetes AwardChuck & BuckBunnyEverything Put TogetherGrooveOur Song
Truer Than Fiction Award
Keep the River on Your Right: A Modern Cannibal Tale
Producers Award
Paul Mezey - The Ballad of Ramblin’ Jack and Spring Forward
- Jim McKay - American Movie and Our Song
- Tim Perell - Louis & Frank and The Myth of Fingerprints
- Diana E. Williams - The Love Machine and Our Song
Marc Forster - Everything Put Together
- Dan McCormack - Other Voices
- Mia Trachinger - ''Bunny''
Films with multiple nominations and awards
| Nominations | Film |
| 5 | Chuck & Buck |
| 5 | Requiem for a Dream |
| 5 | You Can Count on Me |
| 4 | Before Night Falls |
| 4 | George Washington |
| 3 | Crouching Tiger, Hidden Dragon |
| 3 | Love & Basketball |
| 2 | Girlfight |
| 2 | Songcatcher |
| Awards | Film |
| 3 | Crouching Tiger, Hidden Dragon |
| 2 | Requiem for a Dream |
| 2 | You Can Count on Me |