1921–22 Lega Sud
The Southern League was the amatorial football championship in Southern Italy during the 1920s.
The 1921–22 season was the inaugural one of the rebranded league, organized within the Italian Football Confederation. The winner had the honor to play against the Northern Champions.
The League took over the former FIGC Regional championship to improve their quality, adding new regions as Apulia, Sicily and the Marches. As the first step, the League decided to reduce the regional tournaments to ten matchdays for 1922–23 to improve the inter-league playoffs.
Qualifications
Lazio
Tiberis Roma and Vittoria Roma were excluded after 5 rounds, due to irregularities in their subscriptions.These matches were invalidated:
Results table
Relegation tie-breaker in Rome, July 2, 1922: Roman-Audace 2–1.Marche
Football was activated in the Marches in this season.Group A
;Classification| P | Team | Pld | W | D | L | GF | GA | GD | Pts | Promotion or relegation |
| 1. | Helvia Recina | 4 | 4 | 0 | 0 | 11 | 5 | +6 | 8 | Qualified |
| 2. | Macerata | 4 | 2 | 0 | 2 | 9 | 5 | +4 | 4 | Qualified |
| 3. | Virtus Macerata | 4 | 0 | 0 | 4 | 2 | 12 | -10 | 0 | Merged |
Later all clubs merged into new A.C. Maceratese.
;Results table
Group B
;Classification| P | Team | Pld | W | D | L | GF | GA | GD | Pts | Promotion or relegation |
| 1. | Anconitana | 4 | 4 | 0 | 0 | 18 | 2 | +16 | 8 | Qualified |
| 2. | Vigor Senigallia | 4 | 2 | 0 | 2 | 4 | 8 | -4 | 4 | Qualified |
| 3. | Folgore Ancona | 4 | 0 | 0 | 4 | 4 | 16 | -12 | 0 | Merged |
Later Folgore merged with A.C. Ancona.
;Results table
Final round
The results of the matches between sides that were in the same qualification round were valid also for the final round. Due to this, Anconitana and Helvia Recina started the round with a 4-point bonus.;Classification
| P | Team | Pld | W | D | L | GF | GA | GD | Pts | Promotion or relegation |
| 1. | Anconitana | 4 | 4 | 0 | 0 | 18 | 2 | +16 | 12 | Qualified |
| 2. | Vigor Senigallia | 4 | 3 | 1 | 0 | 13 | 6 | +7 | 7 | Eliminated, activated 2nd Division |
| 3. | Helvia Recina | 4 | 0 | 0 | 4 | 3 | 10 | -7 | 4 | Eliminated, activated 2nd Division |
| 4. | Macerata | 4 | 0 | 1 | 3 | 6 | 16 | -10 | 1 | Merged |
;Results table
Sicily
Azzurra Palermo and US Catanese were excluded before the start of the championship.Libertas Palermo, SC Messina and Vigor Trapani retired during the championship and all their remaining matches were considered forfeits.