Small nucleolar RNA SNORD94


In molecular biology, Small Nucleolar RNA SNORD94 is a non-coding RNA molecule which functions in the biogenesis of other small nuclear RNAs. This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA and also often referred to as a guide RNA.
SNOR94 is a member of the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box and the D box. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. SNORD94 is predicted to guide the 2'O-ribose methylation of C62 of the snRNA U6.