Charles Shepard

• Charles Upham Shepard, American mineralogist and chemist
• Charles Biddle Shepard, Congressional Representative from North Carolina
• Charles E. Shepard, American architect based in Kansas City with initials C.E.S., including for design of Charles S. Keith House.
• Charles Shepard Chapman, American painter
• Charles Shepard , English artist and sculptor
• Charles C. Shepard, American microbiologist