Acalypha lyonsii is a shrub up to tall. The leaves are arranged alternately on the twigs and measure up to long by wide. They have rounded teeth on the margins and 4 or 5 lateral veins on either side of the midrib. Flowers are produced from the - male flowers are less than long and are carried on a spike, female flowers are solitary, about in diameter and subtended by a persistent bract about wide. The fruit is a 3-lobed capsule about long and wide.