2000–01 Macedonian First Football League
The 2000–01 Macedonian First League was the 9th season of the Macedonian First Football League, the highest football league of Macedonia. The first matches of the season were played on 20 August 2000 and the last on 27 May 2001. Sloga Jugomagnat defended their championship title, having won their third title in a row. Due to the change of the league structure, the bottom four teams were relegated.